
Gentlemen, please!
This is a SIGNIFICANT decision.
The Big Bang Theory Season 10, Episode 7

They have helped us recover
SIGNIFICANT sums
Game of Thrones Season 7, Episode 4

Only my life.
Not all that SIGNIFICANT, I'm afraid.
Game of Thrones Season 3, Episode 3

...with his dating a woman
whose most SIGNIFICANT achievement...
The Big Bang Theory Season 3, Episode 11

Twenty thousand data runs
and no statistically SIGNIFICANT results.
The Big Bang Theory Season 2, Episode 13